Vanden Bossche MD PhD, Geert
Description
My analysis unambiguously proves that the C-19 mass vaccination experiment has been responsible for selecting and promoting dominant propagation of Om
...
icron in highly C-19 vaccinated populations. Whereas 'original antigenic sin' has been driving immune escape during the pre-Omicron phase of the pandemic in all countries conducting mass C-19 vaccination campaigns, 'SIR' has been responsible for the spectacular evolutionary dynamics of this immune escape pandemic once Omicron dominantly circulated. As Omicron caused SIR-enabling VBTIs and as SIR caused highly C-19 vaccinated populations to exert high immune pressure on more conserved, subdominant S-associated domains, natural selection and dominant propagation of Omicron has been required and sufficient to drive large scale viral immune escape. Continuation of the mass C-19 vaccination program during the Omicron phase of the pandemic has only expedited the selectional adaptive evolution of the virus as booster doses and growing vaccine coverage rates allowed for more frequent and widespread SIR-enabling VBTIs. mRNA-based C-19 vaccines in particular have dramatically accelerated the immune escape dynamics of SC-2 as-in contrast to the other, non-mRNA-based C-19 vaccines-they elicit low-affinity anti-S Abs directed at S protein that is expressed on the surface of the mRNA-transfected host cells.
Read more