Craig H. Mallinckrodt, Geert Molenberghs, Ilya Lipkovich, Bohdana Ratitch
Description
Why estimands are important -- Estimands and how to define them -- Strategies for dealing with intercurrent events -- Real world examples in choosing
...
and specifying estimands -- Causal inference and estimands -- Putting the principles into practice -- Overview of estimators -- Modeling considerations -- Overview of analyses for composite intercurrent event strategies -- Overview of analyses for hypothetical intercurrent event strategies -- Overview of analyses for principal stratification intercurrent event strategies -- Overview of analyses for while-on-treatment intercurrent event strategies -- Overview of analyses for treatment policy intercurrent event strategies -- Missing data -- Sensitivity analyses -- Example data -- Direct maximum likelihood -- Multiple imputation -- Inverse probability weighted generalized estimated equations -- Doubly robust methods -- Reference-based imputation -- Delta adjustment -- Overview of principal stratification methods -- Analytic case study of depression clinical trials -- Analytic case study #2 -- Analytic case study #3.
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Genres
Science & Technology
Research & Essays
Medical & Healthcare
Tags
Reference
Mathematics
Medical
Pharmacology
Technology & Engineering
Chemical & Biochemical
Research
Probability & Statistics
Biostatistics
Reading Moods
No reading moods specified
Contributors
No contributors specified
Publishing Info
Publisher
CRC Press, Taylor & Francis Group
Month-Year
Dec, 2021
ISBN
ISBN-13: 9781032242620
ISBN-10: 1032242620
Language
English
No. of Pages
344
Format
Paperback
Awards & Recognition
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