Donald Y.M. Leung, Malcolm W. Greaves
Description
This state-of-the-science reference provides valuable information on the pathophysiology and economic and social consequences of allergic skin reactio
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ns, as well as new treatments based on emerging concepts of skin disease pathobiology-addressing the epidemiology, mechanisms, occupational effects, environmental triggers, and quality-of-life concerns.
Focuses on atopic dermatitis, urticaria, and allergic contact dermatitis, among other increasingly common skin disorders. Written by more than 35 leading researchers, Allergic Skin Disease
reviews basic principles of the causes of allergic skin responses
analyzes the role of key cell types, effector molecules, cytokines, mediators, chemokines, cell adhesion molecules, and immunogenetic mechanisms
showcases the dynamics of adhesion molecules and the pathophysiology of pruritus
examines clinical features of skin allergies, particularly regarding immune mechanisms that determine pathogenic course and outcome
investigates behaviors of keratinocytes, dendritic cells and macrophages, fibroblasts, lymphocytes, granulocytes, and endothelial cells
explores phototherapy, photochemotherapy, immunomodulatory therapy, and traditional antiinflammatory therapy for recalcitrant skin diseases
discusses anaphylaxis and other allergic reactions to insect bites
surveys demographism, vibratory angioedema, and other types of urticaria
identifies allergic and infectious triggers of skin disease
and more!
Containing over 1800 bibliographic citations, Allergic Skin Disease is a must-read resource for dermatologists, allergists, immunologists, pharmaceutical and cosmetic chemists, internists, pediatricians, and graduate and medical school students in these disciplines.
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M. Dekker